Phase 2 Trial of Pemetrexed in Children and Adolescents with Refractory Solid Tumors: a Children’s Oncology Group Study

BACKGROUND: Pemetrexed is a multi-targeted antifolate that inhibits key enzymes involved in nucleotide biosynthesis. We performed a phase 2 trial of pemetrexed in children with refractory or recurrent solid tumors, including CNS tumors, to estimate the response rate and further define its toxicity p...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Warwick, Anne B., Malempati, Suman, Krailo, Mark, Melemed, Allen, Gorlick, Richard, Ames, Matthew M., Safgren, Stephanie L., Adamson, Peter C., Blaney, Susan M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463652/
https://ncbi.nlm.nih.gov/pubmed/22745043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24244
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы