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Phase I Study of Oxaliplatin and Irinotecan in Pediatric Patients with Refractory Solid Tumors: A Children’s Oncology Group Study

BACKGROUND: This study estimates the maximum tolerated dose (MTD) and describes the toxicities of oxaliplatin combined with irinotecan in children with refractory solid tumors. METHODS: Oxaliplatin was administered on days 1 and 8 in combination with irinotecan on days 1–5 and 8–12 of a 21-day cycle...

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Detalhes bibliográficos
Main Authors: McGregor, Lisa M., Spunt, Sheri L., Furman, Wayne L., Stewart, Clinton F., Schaiquevich, Paula, Krailo, Mark D., Speights, RoseAnne, Ivy, Percy, Adamson, Peter C., Blaney, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897817/
https://ncbi.nlm.nih.gov/pubmed/19170226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24175
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