Phase 2 Trial of Pemetrexed in Children and Adolescents with Refractory Solid Tumors: a Children’s Oncology Group Study

BACKGROUND: Pemetrexed is a multi-targeted antifolate that inhibits key enzymes involved in nucleotide biosynthesis. We performed a phase 2 trial of pemetrexed in children with refractory or recurrent solid tumors, including CNS tumors, to estimate the response rate and further define its toxicity p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Warwick, Anne B., Malempati, Suman, Krailo, Mark, Melemed, Allen, Gorlick, Richard, Ames, Matthew M., Safgren, Stephanie L., Adamson, Peter C., Blaney, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463652/
https://ncbi.nlm.nih.gov/pubmed/22745043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.24244
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados