A RHAMM Mimetic Peptide Blocks Hyaluronan Signaling and Reduces Inflammation and Fibrogenesis in Excisional Skin Wounds

Hyaluronan is activated by fragmentation and controls inflammation and fibroplasia during wound repair and diseases (eg, cancer). Hyaluronan-binding peptides were identified that modify fibrogenesis during skin wound repair. Peptides were selected from 7- to 15mer phage display libraries by panning...

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Autores principales: Tolg, Cornelia, Hamilton, Sara R., Zalinska, Ewa, McCulloch, Lori, Amin, Ripal, Akentieva, Natalia, Winnik, Francoise, Savani, Rashmin, Bagli, Darius J., Luyt, Len G., Cowman, Mary K., McCarthy, Jim B., Turley, Eva A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2012
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463631/
https://ncbi.nlm.nih.gov/pubmed/22889846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.036
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