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Apical Oxidative Hyaluronan Degradation Stimulates Airway Ciliary Beating via RHAMM and RON

Hyaluronan (HA) is synthesized in high-molecular-weight form at the apical pole of airway epithelial cells, covering the luminal surface. When human airway epithelial cells grown and redifferentiated at the air–liquid interface (ALI) were exposed to xanthine/xanthine oxidase (X/XO), ciliary beat fre...

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Detalhes bibliográficos
Main Authors: Manzanares, Dahis, Monzon, Maria-Elena, Savani, Rashmin C., Salathe, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976543/
https://ncbi.nlm.nih.gov/pubmed/17395888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0413OC
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