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Apical Oxidative Hyaluronan Degradation Stimulates Airway Ciliary Beating via RHAMM and RON

Hyaluronan (HA) is synthesized in high-molecular-weight form at the apical pole of airway epithelial cells, covering the luminal surface. When human airway epithelial cells grown and redifferentiated at the air–liquid interface (ALI) were exposed to xanthine/xanthine oxidase (X/XO), ciliary beat fre...

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Autores principales: Manzanares, Dahis, Monzon, Maria-Elena, Savani, Rashmin C., Salathe, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976543/
https://ncbi.nlm.nih.gov/pubmed/17395888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0413OC
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