The MAPK1/3 pathway is essential for the deregulation of autophagy observed in G2019S LRRK2 mutant fibroblasts

The link between the deregulation of autophagy and cell death processes can be essential in the development of several neurodegenerative diseases, such as Parkinson disease (PD). However, the molecular mechanism of deregulation of this degradative process in PD patients is unknown. The leucine-rich...

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Detalhes bibliográficos
Main Authors: Bravo-San Pedro, José M., Gómez-Sánchez, Rubén, Niso-Santano, Mireia, Pizarro-Estrella, Elisa, Aiastui-Pujana, Ana, Gorostidi, Ana, Climent, Vicente, López de Maturana, Rakel, Sanchez-Pernaute, Rosario, López de Munain, Adolfo, Fuentes, José M., González-Polo, Rosa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Autophagic Punctum
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463455/
https://ncbi.nlm.nih.gov/pubmed/22914360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21270
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