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High cell density and productivity culture of Chinese hamster ovary cells in a fluidized bed bioreactor

A recombinant Chinese hamster ovary clone was cultivated in a 2L Cytopilot Mini fluidized bed bioreactor using Cytoline 1 microcarriers and a 10L B. Braun stirred tank bioreactor with Cytodex 1 microcarriers. Cytoline 1 is a macroporous polyethylene microcarrier and Cytodex 1 is a solid DEAE-dextran...

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Bibliografske podrobnosti
Main Authors: Kong, D., Cardak, S., Chen, M., Gentz, R., Zhang, J.
Format: Artigo
Jezik:Inglês
Izdano: Kluwer Academic Publishers 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463391/
https://ncbi.nlm.nih.gov/pubmed/19003344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008064217040
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