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Effect of hypoosmotic pressure on cell growth and antibody production in recombinant Chinese hamster ovary cell culture

To determine the response of recombinant Chinese hamster ovary (rCHO) cells subjected to hypoosmotic pressure, rCHO cells (CS13*–1.0) producing a chimeric antibody were cultivated in the hypoosmolar medium resulting from NaCl subtraction. At hypoosmotic pressure, CS13*–1.0 cells displayed decreased...

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Detalles Bibliográficos
Main Authors: Lee, Moon Sue, Lee, Gyun Min
Formato: Artigo
Idioma:Inglês
Publicado: Kluwer Academic Publishers 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449663/
https://ncbi.nlm.nih.gov/pubmed/19003316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1014032701800
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