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Effect of hypoosmotic pressure on cell growth and antibody production in recombinant Chinese hamster ovary cell culture

To determine the response of recombinant Chinese hamster ovary (rCHO) cells subjected to hypoosmotic pressure, rCHO cells (CS13*–1.0) producing a chimeric antibody were cultivated in the hypoosmolar medium resulting from NaCl subtraction. At hypoosmotic pressure, CS13*–1.0 cells displayed decreased...

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Bibliographic Details
Main Authors: Lee, Moon Sue, Lee, Gyun Min
Format: Artigo
Language:Inglês
Published: Kluwer Academic Publishers 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449663/
https://ncbi.nlm.nih.gov/pubmed/19003316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1014032701800
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