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High cell density and productivity culture of Chinese hamster ovary cells in a fluidized bed bioreactor
A recombinant Chinese hamster ovary clone was cultivated in a 2L Cytopilot Mini fluidized bed bioreactor using Cytoline 1 microcarriers and a 10L B. Braun stirred tank bioreactor with Cytodex 1 microcarriers. Cytoline 1 is a macroporous polyethylene microcarrier and Cytodex 1 is a solid DEAE-dextran...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Kluwer Academic Publishers
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463391/ https://ncbi.nlm.nih.gov/pubmed/19003344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008064217040 |
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