DNA rearrangements in MPC-11 immunoglobulin heavy chain class-switch variants.

Immunoglobulin heavy chain class switching has been observed in vitro. In the IgG2b-producing MPC-11 mouse myeloma cell line, IgG2a-producing cells arise at a high frequency. In some cases, switch variants producing normal-sized (Mr 55,000) gamma 2a heavy chains have arisen spontaneously from a muta...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Eckhardt, L A, Tilley, S A, Lang, R B, Marcu, K B, Birshtein, B K
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1982
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6806822/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.9.3006
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