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Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Degradation by Alkaline Phosphatase

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a ubiquitous second messenger providing a Ca(2+) trigger in a wide range of cell types. However, its metabolism is not well understood. Here, we demonstrate the presence of endogenous NAADP in HeLa cells. CD38, a promiscuous enzyme described t...

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Autors principals: Schmid, Frederike, Fliegert, Ralf, Westphal, Tim, Bauche, Andreas, Guse, Andreas H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463342/
https://ncbi.nlm.nih.gov/pubmed/22851169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362715
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