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Clostridium perfringens Alpha-toxin Recognizes the GM1a-TrkA Complex
Clostridium perfringens alpha-toxin is the major virulence factor in the pathogenesis of gas gangrene. Alpha-toxin is a 43-kDa protein with two structural domains; the N-domain contains the catalytic site and coordinates the divalent metal ions, and the C-domain is a membrane-binding site. The role...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3463319/ https://ncbi.nlm.nih.gov/pubmed/22847002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393801 |
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