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Thermally-induced protein unfolding probed by isotope-edited IR spectroscopy

Infrared (IR) spectroscopy has been widely utilized for the study of protein folding, unfolding and misfolding processes. We have previously developed a theoretical method for calculating IR spectra of proteins in the amide I region. In this work, we apply this method, in combination with replica-ex...

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Detalhes bibliográficos
Main Authors: Wang, Lu, Skinner, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463243/
https://ncbi.nlm.nih.gov/pubmed/22853174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp304613b
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