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Thermal unfolding of the N-terminal region of p53 monitored by circular dichroism spectroscopy
It has been estimated that 30% of eukaryotic protein and 70% of transcription factors are intrinsically disordered (ID). The biochemical significance of proteins that lack stable tertiary structure, however, is not clearly understood, largely owing to an inability to assign well-defined structures t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3527704/ https://ncbi.nlm.nih.gov/pubmed/22915551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2146 |
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