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Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence.

Fluorescein isothiocyanate-conjugated dextran was introduced preferentially into hepatic lysosomes by intraperitoneal injection into rats. The pH in isolated lysosomes, measured by fluorescein fluorescence, was approximately 5 and gradually increased in KCl (to 7.0) at 25 degrees C. In the presence...

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Bibliografiske detaljer
Main Authors: Ohkuma, S, Moriyama, Y, Takano, T
Format: Artigo
Sprog:Inglês
Udgivet: 1982
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC346285/
https://ncbi.nlm.nih.gov/pubmed/6178109
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