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The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells

Pleiotropic effects of leptin have been identified in reproduction and pregnancy, particularly in the placenta, where it works as an autocrine hormone. In this work, we demonstrated that human chorionic gonadotropin (hCG) added to JEG-3 cell line or to placental explants induces endogenous leptin ex...

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Detalhes bibliográficos
Main Authors: Maymó, Julieta Lorena, Pérez Pérez, Antonio, Maskin, Bernardo, Dueñas, José Luis, Calvo, Juan Carlos, Sánchez Margalet, Víctor, Varone, Cecilia Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462743/
https://ncbi.nlm.nih.gov/pubmed/23056265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046216
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