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The Alternative Epac/cAMP Pathway and the MAPK Pathway Mediate hCG Induction of Leptin in Placental Cells

Pleiotropic effects of leptin have been identified in reproduction and pregnancy, particularly in the placenta, where it works as an autocrine hormone. In this work, we demonstrated that human chorionic gonadotropin (hCG) added to JEG-3 cell line or to placental explants induces endogenous leptin ex...

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Autors principals: Maymó, Julieta Lorena, Pérez Pérez, Antonio, Maskin, Bernardo, Dueñas, José Luis, Calvo, Juan Carlos, Sánchez Margalet, Víctor, Varone, Cecilia Laura
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462743/
https://ncbi.nlm.nih.gov/pubmed/23056265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046216
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