An iron-dependent and transferrin-mediated cellular uptake pathway for plutonium

Plutonium is a toxic synthetic element with no natural biological function, but it is strongly retained by humans when ingested. Using small angle X-ray scattering, receptor binding assays, and synchrotron X-ray fluorescence microscopy we find that rat adrenal gland (PC12) cells can acquire plutoniu...

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Main Authors: Jensen, Mark P., Gorman-Lewis, Drew, Aryal, Baikuntha, Paunesku, Tatjana, Vogt, Stefan, Rickert, Paul G., Seifert, Soenke, Lai, Barry, Woloschak, Gayle E., Soderholm, L.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462652/
https://ncbi.nlm.nih.gov/pubmed/21706034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.594
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