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Nanocarriers Enhance Doxorubicin Uptake in Drug-Resistant Ovarian Cancer Cells

Resistance to anthracyclines and other chemotherapeutics due to P-glycoprotein (PGP)-mediated export is a frequent problem in cancer treatment. Here we report that iron oxide-titanium dioxide core-shell nanocomposites can serve as efficient carriers for doxorubicin to overcome this common mechanism...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Arora, Hans C, Jensen, Mark P, Yuan, Ye, Wu, Aiguo, Vogt, Stefan, Paunesku, Tatjana, Woloschak, Gayle E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657469/
https://ncbi.nlm.nih.gov/pubmed/22158944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2890
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