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Nanocarriers Enhance Doxorubicin Uptake in Drug-Resistant Ovarian Cancer Cells

Resistance to anthracyclines and other chemotherapeutics due to P-glycoprotein (PGP)-mediated export is a frequent problem in cancer treatment. Here we report that iron oxide-titanium dioxide core-shell nanocomposites can serve as efficient carriers for doxorubicin to overcome this common mechanism...

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Detalhes bibliográficos
Main Authors: Arora, Hans C, Jensen, Mark P, Yuan, Ye, Wu, Aiguo, Vogt, Stefan, Paunesku, Tatjana, Woloschak, Gayle E
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657469/
https://ncbi.nlm.nih.gov/pubmed/22158944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-2890
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