Načítá se...

Co-Stimulation Modulation with Abatacept in Patients with Recent-Onset Type 1 Diabetes: A Randomised Double-Masked Controlled Trial

BACKGROUND: The immunopathogenesis of type 1 diabetes mellitus (T1DM) is associated with T-lymphocyte autoimmunity. To be fully active, immune T-lymphocytes require a co-stimulatory signal in addition to the main antigen driven signal. Abatacept modulates co-stimulation andprevents full T-lymphocyte...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Orban, Tihamer, Bundy, Brian, Becker, Dorothy J., DiMeglio, Linda A., Gitelman, Stephen E., Goland, Robin, Gottlieb, Peter A., Greenbaum, Carla J., Marks, Jennifer B., Monzavi, Roshanak, Moran, Antoinette, Raskin, Philip, Rodriguez, Henry, Russell, William E., Schatz, Desmond, Wherrett, Diane, Wilson, Darrell M., Krischer, Jeffrey P., Skyler, Jay S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462593/
https://ncbi.nlm.nih.gov/pubmed/21719096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(11)60886-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!