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Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA(1c) in New-Onset Type 1 Diabetes

OBJECTIVE: A pilot study suggested that combination therapy with low-dose anti-thymocyte globulin (ATG) and pegylated granulocyte colony-stimulating factor (GCSF) preserves C-peptide in established type 1 diabetes (T1D) (duration 4 months to 2 years). We hypothesized that 1) low-dose ATG/GCSF or 2)...

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Foilsithe in:Diabetes Care
Main Authors: Haller, Michael J., Schatz, Desmond A., Skyler, Jay S., Krischer, Jeffrey P., Bundy, Brian N., Miller, Jessica L., Atkinson, Mark A., Becker, Dorothy J., Baidal, David, DiMeglio, Linda A., Gitelman, Stephen E., Goland, Robin, Gottlieb, Peter A., Herold, Kevan C., Marks, Jennifer B., Moran, Antoinette, Rodriguez, Henry, Russell, William, Wilson, Darrell M., Greenbaum, Carla J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Diabetes Association 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105329/
https://ncbi.nlm.nih.gov/pubmed/30012675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc18-0494
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