Human lupus serum induces neutrophil mediated organ damage in mice that is enabled by Mac-1 deficiency()

Systemic lupus erythematosus (SLE) is a chronic, multi-organ inflammatory autoimmune disorder associated with high levels of circulating autoantibodies and immune complexes. We report that passive transfer of human SLE sera into mice expressing the uniquely human FcγRIIA and FcγRIIIB on neutrophils...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Rosetti, Florencia, Tsuboi, Naotake, Chen, Kan, Nishi, Hiroshi, Ernandez, Thomas, Sethi, Sanjeev, Croce, Kevin, Stavrakis, George, Alcocer-Varela, Jorge, Gomez-Martin, Diana, van Rooijen, Nico, Kyttaris, Vasileios C., Lichtman, Andrew, Tsokos, George C., Mayadas, Tanya N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462585/
https://ncbi.nlm.nih.gov/pubmed/22933624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201594
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk