Human lupus serum induces neutrophil mediated organ damage in mice that is enabled by Mac-1 deficiency()

Systemic lupus erythematosus (SLE) is a chronic, multi-organ inflammatory autoimmune disorder associated with high levels of circulating autoantibodies and immune complexes. We report that passive transfer of human SLE sera into mice expressing the uniquely human FcγRIIA and FcγRIIIB on neutrophils...

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Detalhes bibliográficos
Main Authors: Rosetti, Florencia, Tsuboi, Naotake, Chen, Kan, Nishi, Hiroshi, Ernandez, Thomas, Sethi, Sanjeev, Croce, Kevin, Stavrakis, George, Alcocer-Varela, Jorge, Gomez-Martin, Diana, van Rooijen, Nico, Kyttaris, Vasileios C., Lichtman, Andrew, Tsokos, George C., Mayadas, Tanya N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462585/
https://ncbi.nlm.nih.gov/pubmed/22933624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201594
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