Carbohydrate Composition of Amphiphilic Macromolecules Influences Physicochemical Properties and Binding to Atherogenic Scavenger Receptor A

Amphiphilic macromolecules (AMs) based on carbohydrate domains functionalized with poly(ethylene glycol) can inhibit the uptake of oxidized low density lipoprotein (oxLDL) mediated by scavenger receptor A (SR-A) and counteract foam cell formation, the characteristic “atherosclerotic” phenotype. A se...

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Detalhes bibliográficos
Main Authors: Hehir, Sarah, Plourde, Nicole M., Gu, Li, Poree, Dawanne E., Welsh, William J., Moghe, Prabhas V., Uhrich, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462273/
https://ncbi.nlm.nih.gov/pubmed/22835678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2012.07.022
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