Structure Activity Relations of Nanolipoblockers with the Atherogenic Domain of Human Macrophage Scavenger Receptor A

Oxidized low density lipoprotein (oxLDL) uptake by macrophages is mediated by scavenger receptors and leads to unregulated cholesterol accumulation. Micellar nanolipoblockers (NLBs) consist of alkyl chains and polyethylene glycol on mucic acid. NLBs functionalized with anionic groups inhibit oxLDL u...

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Hlavní autoři: Plourde, Nicole, Kortagere, Sandhya, Welsh, William, Moghe, Prabhas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716033/
https://ncbi.nlm.nih.gov/pubmed/19405544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm8014522
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