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E2F-1 lacking the transcriptional activity domain induces autophagy
The transcription factor E2F-1 plays a crucial role in the control of cell proliferation. E2F-1 has tumor suppressive properties by inducing apoptosis and autophagy. In this study, E2F-1 and its truncated form (E2Ftr), lacking the transactivation domain (TAD), were compared for their ability to indu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462036/ https://ncbi.nlm.nih.gov/pubmed/22825328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21143 |
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