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Rhodium(iii)-catalyzed synthesis of phthalides by cascade addition and cyclization of benzimidates with aldehydes
We herein report the Rh(iii)-catalyzed C–H bond activation and addition of benzimidates to aldehydes to afford biologically important phthalides in a single step. The imidate is a novel and unexplored directing group that not only enables C–H bond activation and addition to aldehydes, but also serve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462028/ https://ncbi.nlm.nih.gov/pubmed/23050074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC20835K |
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