Mutant huntingtin fragmentation in immune cells tracks Huntington’s disease progression

Huntington’s disease (HD) is a fatal, inherited neurodegenerative disorder caused by an expanded CAG repeat in the gene encoding huntingtin (HTT). Therapeutic approaches to lower mutant HTT (mHTT) levels are expected to proceed to human trials, but noninvasive quantification of mHTT is not currently...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Weiss, Andreas, Träger, Ulrike, Wild, Edward J., Grueninger, Stephan, Farmer, Ruth, Landles, Christian, Scahill, Rachael I., Lahiri, Nayana, Haider, Salman, Macdonald, Douglas, Frost, Chris, Bates, Gillian P., Bilbe, Graeme, Kuhn, Rainer, Andre, Ralph, Tabrizi, Sarah J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2012
Onderwerpen:
Brief Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461928/
https://ncbi.nlm.nih.gov/pubmed/22996692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64565
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items