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Cytokeratins mediate epithelial innate defense through their antimicrobial properties

Epithelial cells express antimicrobial proteins in response to invading pathogens, although little is known regarding epithelial defense mechanisms during healthy conditions. Here we report that epithelial cytokeratins have innate defense properties because they constitutively produce cytoprotective...

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Detalhes bibliográficos
Main Authors: Tam, Connie, Mun, James J., Evans, David J., Fleiszig, Suzanne M.J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461926/
https://ncbi.nlm.nih.gov/pubmed/23006328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64416
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