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MicroRNA-762 Is Upregulated in Human Corneal Epithelial Cells in Response to Tear Fluid and Pseudomonas aeruginosa Antigens and Negatively Regulates the Expression of Host Defense Genes Encoding RNase7 and ST2

Mucosal surfaces regulate defenses against infection and excessive inflammation. We previously showed that human tears upregulated epithelial expression of genes encoding RNase7 and ST2, which inhibited Pseudomonas aeruginosa invasion of human corneal epithelial cells. Here, microRNA microarrays wer...

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Detalhes bibliográficos
Main Authors: Mun, James, Tam, Connie, Chan, Gary, Kim, Jong Hun, Evans, David, Fleiszig, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585208/
https://ncbi.nlm.nih.gov/pubmed/23469087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057850
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