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Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence

We previously showed that ADP-ribosylation (ADP-r) activity of ExoS, a type III secreted toxin of Pseudomonas aeruginosa, enables bacterial replication in corneal and respiratory epithelial cells and correlates with bacterial trafficking to plasma membrane blebs (bleb-niche formation). Here, we expl...

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Detalhes bibliográficos
Main Authors: Hritonenko, Victoria, Mun, James J., Tam, Connie, Simon, Nathan C., Barbieri, Joseph T., Evans, David J., Fleiszig, Suzanne M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213052/
https://ncbi.nlm.nih.gov/pubmed/21843628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2011.08.001
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