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GATA4 and GATA6 control mouse pancreas organogenesis

Recently, heterozygous mutations in GATA6 have been found in neonatal diabetic patients with failed pancreatic organogenesis. To investigate the roles of GATA4 and GATA6 in mouse pancreas organogenesis, we conditionally inactivated these genes within the pancreas. Single inactivation of either gene...

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書目詳細資料
Main Authors: Carrasco, Manuel, Delgado, Irene, Soria, Bernat, Martín, Francisco, Rojas, Anabel
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461915/
https://ncbi.nlm.nih.gov/pubmed/23006330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63240
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