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GATA4 and GATA6 control mouse pancreas organogenesis

Recently, heterozygous mutations in GATA6 have been found in neonatal diabetic patients with failed pancreatic organogenesis. To investigate the roles of GATA4 and GATA6 in mouse pancreas organogenesis, we conditionally inactivated these genes within the pancreas. Single inactivation of either gene...

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Bibliografische gegevens
Hoofdauteurs: Carrasco, Manuel, Delgado, Irene, Soria, Bernat, Martín, Francisco, Rojas, Anabel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461915/
https://ncbi.nlm.nih.gov/pubmed/23006330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63240
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