Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

Pancreatic agenesis is a human disorder caused by defects in pancreas development. To date, only a few genes have been linked to pancreatic agenesis in humans, with mutations in pancreatic and duodenal homeobox 1 (PDX1) and pancreas-specific transcription factor 1a (PTF1A) reported in only 5 familie...

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Détails bibliographiques
Auteurs principaux: Xuan, Shouhong, Borok, Matthew J., Decker, Kimberly J., Battle, Michele A., Duncan, Stephen A., Hale, Michael A., Macdonald, Raymond J., Sussel, Lori
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461916/
https://ncbi.nlm.nih.gov/pubmed/23006325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63352
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