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GATA4 and GATA6 control mouse pancreas organogenesis
Recently, heterozygous mutations in GATA6 have been found in neonatal diabetic patients with failed pancreatic organogenesis. To investigate the roles of GATA4 and GATA6 in mouse pancreas organogenesis, we conditionally inactivated these genes within the pancreas. Single inactivation of either gene...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461915/ https://ncbi.nlm.nih.gov/pubmed/23006330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63240 |
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