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GATA4 and GATA6 control mouse pancreas organogenesis

Recently, heterozygous mutations in GATA6 have been found in neonatal diabetic patients with failed pancreatic organogenesis. To investigate the roles of GATA4 and GATA6 in mouse pancreas organogenesis, we conditionally inactivated these genes within the pancreas. Single inactivation of either gene...

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Bibliografiske detaljer
Main Authors: Carrasco, Manuel, Delgado, Irene, Soria, Bernat, Martín, Francisco, Rojas, Anabel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461915/
https://ncbi.nlm.nih.gov/pubmed/23006330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63240
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