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GATA4 and GATA6 control mouse pancreas organogenesis

Recently, heterozygous mutations in GATA6 have been found in neonatal diabetic patients with failed pancreatic organogenesis. To investigate the roles of GATA4 and GATA6 in mouse pancreas organogenesis, we conditionally inactivated these genes within the pancreas. Single inactivation of either gene...

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Detaylı Bibliyografya
Asıl Yazarlar: Carrasco, Manuel, Delgado, Irene, Soria, Bernat, Martín, Francisco, Rojas, Anabel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461915/
https://ncbi.nlm.nih.gov/pubmed/23006330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63240
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