Role of microRNA Processing in Adipose Tissue in Stress Defense and Longevity

Excess adipose tissue is associated with metabolic disease and reduced lifespan, whereas caloric restriction decreases these risks. Here we show that as mice age, there is down-regulation of Dicer and miRNA processing in adipose tissue resulting in decreases of multiple miRNAs. A similar decline of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mori, Marcelo A., Raghavan, Prashant, Thomou, Thomas, Boucher, Jeremie, Robida-Stubbs, Stacey, Macotela, Yazmin, Russell, Steven J., Kirkland, James L., Blackwell, T. Keith, Kahn, C. Ronald
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461823/
https://ncbi.nlm.nih.gov/pubmed/22958919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.07.017
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi