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The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy

DNA damaging agents such as radiotherapy and gemcitabine are frequently used for the treatment of pancreatic cancer. However, these treatments typically provide only modest benefit. Improving the low survival rate for pancreatic cancer patients therefore remains a major challenge in oncology. Inhibi...

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Detalhes bibliográficos
Main Authors: Prevo, Remko, Fokas, Emmanouil, Reaper, Philip M., Charlton, Peter A., Pollard, John R., McKenna, W. Gillies, Muschel, Ruth J., Brunner, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461814/
https://ncbi.nlm.nih.gov/pubmed/22825331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.21093
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