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Transcription of the Tumor Suppressor Genes p53 and RB in Lymphocytes from Patients with Chronic Kidney Disease: Evidence of Molecular Senescence?

Patients suffering from renal failure exhibit an impaired immune system function. We wanted to investigate the transcription of the tumor suppressor genes p53 and RB to record, if these cells could be stimulated in vitro in order to divide, after the addition of antigenic and inflammatory factors. T...

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Detalhes bibliográficos
Main Authors: Kordinas, Vasileios, Nicolaou, Chryssoula, Tsirpanlis, George, Ioannidis, Anastasios, Bersimis, Sotiris, Sabanis, Nikos, Fragou, Eleni, Tsiolaki, Konstantina, Chatzipanagiotou, Stylianos
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461626/
https://ncbi.nlm.nih.gov/pubmed/23050148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/154397
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