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Transcription of the Tumor Suppressor Genes p53 and RB in Lymphocytes from Patients with Chronic Kidney Disease: Evidence of Molecular Senescence?

Patients suffering from renal failure exhibit an impaired immune system function. We wanted to investigate the transcription of the tumor suppressor genes p53 and RB to record, if these cells could be stimulated in vitro in order to divide, after the addition of antigenic and inflammatory factors. T...

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Detalles Bibliográficos
Principais autores: Vasileios Kordinas, Chryssoula Nicolaou, George Tsirpanlis, Anastasios Ioannidis, Sotiris Bersimis, Nikos Sabanis, Eleni Fragou, Konstantina Tsiolaki, Stylianos Chatzipanagiotou
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2012-01-01
Series:International Journal of Nephrology
Acceso en liña:http://dx.doi.org/10.1155/2012/154397
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