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Effect of the VKORC1 D36Y variant on warfarin dose requirement and pharmacogenetic dose prediction

Pharmacogenetic dosing algorithms help predict warfarin maintenance doses, but their predictive performance differs in different populations, possibly due to unsuspected population-specific genetic variants. The objectives of this study were to quantify the effect of the VKORC1 D36Y variant (a marke...

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Bibliografske podrobnosti
Main Authors: Kurnik, D., Qasim, H., Sominsky, S., Lubetsky, A., Markovits, N., Li, C., Stein, C. M., Halkin, H., Gak, E., Loebstein, R.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461592/
https://ncbi.nlm.nih.gov/pubmed/22871975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-03-0151
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