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Solubilization and purification of the alpha 1-adrenergic receptor using a novel affinity resin.

The highly selective alpha 1-adrenergic receptor antagonist prazosin was used to identify binding sites having alpha-adrenergic specificity in rat hepatic plasma membranes. Solubilization of the membrane-bound receptors was achieved by incubation with the nonionic detergent digitonin, and binding ac...

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Bibliografski detalji
Glavni autori: Graham, R M, Hess, H J, Homcy, C J
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC346155/
https://ncbi.nlm.nih.gov/pubmed/6285370
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