Photoaffinity labeling of the porcine brain alpha 2-adrenergic receptor using a radioiodinated arylazide derivative of rauwolscine: identification of the hormone-binding subunit.

A functionalized derivative of the alpha 2-selective antagonist rauwolscine formed the basis for a photoaffinity adduct that has allowed identification of the hormone-binding subunit of the brain alpha 2-adrenergic receptor protein. Rauwolscine carboxylate underwent reaction with 4-N-t-butyloxycarbo...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Lanier, S M, Graham, R M, Hess, H J, Grodski, A, Repaske, M G, Nunnari, J M, Limbird, L E, Homcy, C J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387137/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9358
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