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Overexpression of HIF Prolyl-Hydoxylase-2 transgene in the renal medulla induced a salt sensitive hypertension

Renal medullary hypoxia-inducible factor (HIF)-1α and its target genes, such as haem oxygenase and nitric oxide synthase, have been indicated to play an important role in the regulation of sodium excretion and blood pressure. HIF prolyl hydroxylase domain-containing proteins (PHDs) are major enzymes...

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Detalhes bibliográficos
Main Authors: Zhu, Qing, Liu, Miao, Han, Wei-Qing, Li, Pin-Lan, Wang, Zhengchao, Li, Ningjun
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461349/
https://ncbi.nlm.nih.gov/pubmed/22686466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01590.x
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