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Overexpression of HIF-1α Transgene in the Renal Medulla Attenuated Salt Sensitive Hypertension in Dahl S Rats

Hypoxia inducible factor (HIF)-1α-mediated gene activation in the renal medulla in response to high salt intake plays an important role in the control of salt sensitivity of blood pressure. High salt-induced activation of HIF-1α in the renal medulla is blunted in Dahl S rats. The present study deter...

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Hlavní autoři: Zhu, Qing, Wang, Zhengchao, Xia, Min, Li, Pin-Lan, Zhang, Fan, Li, Ningjun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402054/
https://ncbi.nlm.nih.gov/pubmed/22349312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.02.002
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