MeCP2 Is Critical for Maintaining Mature Neuronal Networks and Global Brain Anatomy during Late Stages of Postnatal Brain Development and in the Mature Adult Brain

Mutations in the X-linked gene, methyl-CpG binding protein 2 (Mecp2), underlie a wide range of neuropsychiatric disorders, most commonly, Rett Syndrome (RTT), a severe autism spectrum disorder that affects approximately one in 10,000 female live births. Because mutations in the Mecp2 gene occur in t...

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Main Authors: Nguyen, Minh Vu Chuong, Du, Fang, Felice, Christy A., Shan, Xiwei, Nigam, Aparna, Mandel, Gail, Robinson, John K., Ballas, Nurit
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461266/
https://ncbi.nlm.nih.gov/pubmed/22815516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1316-12.2012
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