Engagement of Siglec-7 Receptor Induces a Pro-Inflammatory Response Selectively in Monocytes

Sialic acid binding immunoglobulin-like lectin-7 (Siglec-7) is a trans-membrane receptor carrying immunoreceptor tyrosine based inhibitory motifs (ITIMs) and delivering inhibitory signals upon ligation with sialylated glycans. This inhibitory function can be also targeted by several pathogens that h...

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Библиографические подробности
Главные авторы: Varchetta, Stefania, Brunetta, Enrico, Roberto, Alessandra, Mikulak, Joanna, Hudspeth, Kelly L., Mondelli, Mario U., Mavilio, Domenico
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461047/
https://ncbi.nlm.nih.gov/pubmed/23029261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045821
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