The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer–cell subsets associated with high levels of HIV-1 viremia

HIV-1 has developed several strategies to evade natural killer (NK)–cell antiviral functions. One of these mechanisms is the HIV-1–induced expansion of highly dysfunctional NK-cell subsets. Here, we analyze a large cohort of HIV-1–infected patients in early or chronic phases of infection, both cross...

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Detalhes bibliográficos
Main Authors: Brunetta, Enrico, Fogli, Manuela, Varchetta, Stefania, Bozzo, Luisa, Hudspeth, Kelly L., Marcenaro, Emanuela, Moretta, Alessandro, Mavilio, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773483/
https://ncbi.nlm.nih.gov/pubmed/19710502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-226332
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