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Engagement of Siglec-7 Receptor Induces a Pro-Inflammatory Response Selectively in Monocytes
Sialic acid binding immunoglobulin-like lectin-7 (Siglec-7) is a trans-membrane receptor carrying immunoreceptor tyrosine based inhibitory motifs (ITIMs) and delivering inhibitory signals upon ligation with sialylated glycans. This inhibitory function can be also targeted by several pathogens that h...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461047/ https://ncbi.nlm.nih.gov/pubmed/23029261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045821 |
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