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Up-Regulation of TIMP-1 by Genipin Inhibits MMP-2 Activities and Suppresses the Metastatic Potential of Human Hepatocellular Carcinoma

AIM OF THE STUDY: Hepatocellular carcinoma is one of the most malignant human cancers with high metastatic potential. The aim of this study is to investigate the anti-metastatic effect of genipin and its underlying mechanism. EXPERIMENTAL APPROACH: The anti-metastatic potential of genipin was evalua...

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Detalhes bibliográficos
Main Authors: Wang, Ning, Zhu, Meifen, Tsao, Sai-Wah, Man, Kwan, Zhang, Zhangjin, Feng, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461024/
https://ncbi.nlm.nih.gov/pubmed/23029478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046318
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